![]() ![]() Revolutions in computing Find out how scientists are exploiting digital technologies to understand online behaviour and drive research progress.Nanotechnology in action The challenges and opportunities of turning advances in nanotechnology into commercial products.#BlackInPhysics Celebrating Black physicists and revealing a more complete picture of what a physicist looks like.Artificial intelligence Explore the ways in which today’s world relies on AI, and ponder how this technology might shape the world of tomorrow.Collections Explore special collections that bring together our best content on trending topics.Innovation showcases A round-up of the latest innovation from our corporate partners.Projects and facilities Follow the latest progress at the world’s top scientific experiments.Policy and funding Understand how emerging policy changes could affect your work and career.Education and outreach Learn about novel approaches to educating and inspiring the scientists of the future.Business and innovation Find out how recent scientific breakthroughs are driving business innovation and commercial growth.Impact Explore the value of scientific research for industry, the economy and society.Personalities Find out who’s doing what in industry and academia.Interviews Discover the views of leading figures in the scientific community.Opinion and reviews Find out whether you agree with our expert commentators.Careers Consider your career options with valuable advice and insightful case studies.People Meet the people behind the science.Events Plan the meetings and conferences you want to attend with our comprehensive events calendar.Blog Enjoy a more personal take on the key events in and around science.Analysis Discover the stories behind the headlines.Features Take a deeper look at the emerging trends and key issues within the global scientific community.News Stay informed about the latest developments that affect scientists in all parts of the world.Research updates Keep track of the most exciting research breakthroughs and technology innovations.Latest Explore all the latest news and information on Physics World.Gelin, L.-E., and Ingelman, B., Acta Chir. by Eiseman, B., and Bosomworth, P.), 6 and 25 (Division of Medical Sciences, National Research Council, Washington, DC, 1963).īergenty, S.-E., Gelin, L.-E., Rudenstam, C.-M., and Zederfeldt, B., Acta Chir. Med., 270, 832 270, 839 (1964).Įvaluation of Low Molecular Weight Dextran in Shock: Pharmacology and Pertinent Rheology (edit. Nevertheless, some workers still feel that infusions of dextran-40 are of special value in the treatment of hyperviscous states, and that the beneficial effects of this agent are mediated, at least in part, through the dissolution of RBC aggregates 7.ĭintenfass, L., Arch. Indeed, many investigators have concluded that all the beneficial effects of dextran-40 can be ascribed to blood dilution 8,10–14, and evidence has appeared showing that this agent, like dextrans of higher molecular weight, will actually increase blood viscosity if the haematocrit is not permitted to fall 3,10,12,15. The evaluation of dextran-40 is complicated, however, by the multiplicity of its effects, and particularly by its ability to expand the volume of plasma and reduce the haematocrit, alterations which in themselves lower blood viscosity 1,2,3,4,6–8. Solutions of this type of dextran, with an average molecular weight of 40,000 (also known as low molecular weight dextran 8, low viscosity dextran 4,5 and ‘Rheomacrodex’ 6), were said to reduce blood viscosity by inhibiting or reversing the formation of erythrocyte (RBC) aggregates 1–7 the presence of which is thought to contribute to the elevated viscosity levels found in pathological states 1,2. Dextran-40 has been thought to be unique in performing this function 3–7, but since its introduction as a plasma expander it has been the object of controversy because of conflicting reports about both its actual effect on viscosity and its mode of action 2,3,7–14. This rise may compromise the perfusion and nutrition of organs throughout the body 1–3 therefore there is great interest in any agent capable of reducing blood viscosity. BLOOD viscosity may be raised in many diseases.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |